[论著]苓芍枣仁颗粒联合酒石酸托特罗定片治疗女性膀胱过度活动症疗效分析

Time:2016-02-22 00:20:07 来源:100091 北京,中国中医科学院西苑医院泌尿外科等 作者:邵魁卿 李奇 曾凡雄 李丁 高瞻 沈建武

《国际中医中药杂志》[ISSN:1673-4246/CN:CN11-5398/R]

卷: 36 期数: 2014年10期

页码: 883-885

栏目: 论著

出版日期: 2014-10-05

文章信息/Info

Title: Combination of Lingshao-Zaoren particle and Tolterodine Tartrate tablets for the treatment of overactive bladder in women

作者: 邵魁卿 李奇 曾凡雄 李丁 高瞻 沈建武 100091 北京,中国中医科学院西苑医院泌尿外科

Author(s): Shao Kuiqing' target="_blank" rel="external"> Shao Kuiqing;  Li Qi;  Zeng FanXiong;  Li Ding;  Gao Zhan; ' target="_blank" rel="external"> Shen Jianwu Department of Urology, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing100091, China

关键词: 苓芍枣仁颗粒; 酒石酸托特罗定片; 膀胱过度活动症; 尿急

Keywords: Lingshao-Zaoren particle' target="_blank" rel="external">Lingshao-Zaoren particle; Tolterodine tartrate tablet; Overactive bladder syndrome; Urgent urination

DOI: 10.3760/cma.j.issn.1673-4246.2014.10.006

摘要: 目的 评价苓芍枣仁颗粒联合酒石酸托特罗定片治疗女性膀胱过度活动症(overactive bladder,OAB)的有效性。方法 收集2012年12月至2013年7月中国中医科学院西苑医院泌尿外科女性膀胱过度活动症门诊患者50例,按随机数字表法将患者分为两组各25例。对照组采用酒石酸托特罗定片治疗,治疗组在对照组治疗基础上配合苓芍枣仁颗粒治疗,两组均治疗4周后,通过膀胱过度活动症状量表(OBASS)和尿急量表的评分比较,评价两组患者的临床疗效。结果 同组治疗前后OBASS评分[治疗组分别为(12.16±1.39)分、(3.24±0.61)分,对照组分别为(13.12±1.45)分、(8.81±1.55)分]比较,差异有统计学意义(P<0.01);尿急量表评分[治疗组分别为(3.99±0.78)分、(1.04±0.72)分,对照组分别为(4.01±0.71)分、(2.61±0.88)分]比较,差异有统计学意义(P<0.01)。两组治疗后OABSS评分、尿急评分比较,差异均有统计学意义(P均<0.01)。结论 苓芍枣仁颗粒联合酒石酸托特罗定片治疗膀胱过度活动症的效果优于单用酒石酸托特罗定片。

Abstract: Objective To evaluate the efficacy of Lingshao-Zaoren particle combined with Tolterodine Tartrate tablet in the treatment of overactive bladder in women. Methods A total of fifty female patients diagnosed with overactive bladder were randomized to receiving Lingshao-Zaoren particle combined with Tolterodine Tartrate tablet group (treatment group, n=25) or only Tolterodine Tartrate tablet group (control group, n=25). Both groups were treated for 4 weeks. Changes of scores from the Overactive Bladder Symptom Scale (OBASS) and the Urgent Urination Scale were assessed. Results The scores from the OBASS improved significantly after treatment than those before treatment in both groups (in the treatment group: 3.24±0.61 vs. 12.16±1.39, P<0.01; in the control group: 8.81±1.55 vs. 13.12±1.45, P<0.01) and so did the Urgent Urination Scale (in the treatment group: 1.04±0.72 vs. 3.99±0.78, P<0.01; in the control group: 2.61±0.88 vs. 4.01±0.71, P<0.01) . There were significantly greater improvements in the scores from the OBASS and the Urgent Urination Scale in the treatment group than those in the control group (all P<0.01). Conclusion Lingshao-Zaoren particle combined with Tolterodine Tartrate tablet was superior to only Tolterodine Tartrate tablet for the treatment of overactive bladder in women.

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