[论著]基于583首中药内服方探讨2型糖尿病用药规律

Time:2016-02-22 00:57:10 来源:210029南京中医药大学[朱苏平(2013级硕士研究生)];210029 南京,江苏省中医院内分泌科(戴芳芳)等 作者:朱苏平 戴芳芳

《国际中医中药杂志》[ISSN:1673-4246/CN:CN11-5398/R]

卷: 38 期数: 2016年01期

页码: 72-75

栏目: 论著

出版日期: 2016-01-11

文章信息/Info

Title: Explore the pathogenesis of type 2 diabetes based on 583 internal medicine parties

作者: 朱苏平 戴芳芳 210029南京中医药大学[朱苏平(2013级硕士研究生)];210029 南京,江苏省中医院内分泌科(戴芳芳)

Author(s): Zhu Suping' target="_blank" rel="external"> Zhu Suping*;  Dai Fangfang. ' target="_blank" rel="external"> Dai Fangfang. * Nanjing University of Chinese Medicine, Nanjing 210029, China

关键词: 糖尿病; 2型; 方剂分析; 计算机辅助; 中医病因和病机; 用药规律

Keywords: Diabetes mellitus;  type 2;  Formula analysis;  computer assisted;  Etiological factors and pathogenesis (TCM);  Medication regularity

DOI: 10.3760/cma.j.issn.1673-4246.2016.01.018

摘要: 目的 通过对江苏省中医院内分泌科门诊数据的收集整理与分析,探讨2型糖尿病中医用药规律。方法 收集2014年1-10月就诊于江苏省中医院内分泌科门诊符合2型糖尿病诊断、使用中药内服方2周以上且降糖有效患者的中药口服方,将方剂中的单味药建立数据库,统计出现频次、频率及其临床功效。结果 共收集583首方剂,含有药物281味,其中使用频次≥30次的药物共107味,以茯苓、白芍、黄芪使用频次最高。这107味中药的临床功效分属10种,其中补益药及清热药所占比重最高(频率分别为30.4%、22.2%),活血化瘀药、利水渗湿药及理气药其次。结论 2型糖尿病的病机主要以“阴津亏耗、燥热为盛”为主,兼“血瘀、痰湿、气滞”,治以滋阴清热为第一要法,注重活血化瘀药、利水渗湿、疏肝理气药的应用。

Abstract: Objective Through the analysis of endocrinology outpatient data of Jiangsu provincial hospital, the law and the pathogenesis of TCM for type 2 diabetes was discussed. Methods The data of patients who were diagnosed of type 2 diabetes in Jiangsu provincial hospital outpatient in January 2014 - October 2014 were collected, which including the oral medicine, establishment of a database, statistical analysis of single herb drugs appear frequency and its clinical efficacy. Results We collected a total of 583 prescriptions which contain 281 kinds of medcicines. Among these medicines, 107 medicines were used more than 30 times, with the most frequently used medicines were poria, root of herbaceous peony and Astragalus. The clinical efficacy of these 107 medicines belonged to 10 kinds, medinces with the tonics and antipyretic functions occupied highest proportion(frequency of 30.4%, 22.2%), followed by promoting blood circulation, diuretics for eliminating dampness, and promoting qi flow. Conclusions The pathogenesis of type 2 diabetes was mainly deficieny of both yin and fluid, and dryness heat inside, accompanied by blood stasis, phlegm, Qi stagnation. Therefore the treatment should be nourishing yin and clearing away heat, besides invigorating blood circulation and eliminating stasis, removing dampness and promoting diuresis, and disperse the depressed liver Qi.

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