[论著]基于中医传承辅助系统分析高忠英治疗慢性萎缩性胃炎的用药规律

Time:2016-02-22 00:57:12 来源:100069 北京,首都医科大学中医药学院(张秋霞、姚晓泉、常佳慧、陆跃);100700 北京,中国中医科学院博士后流动站(张秋霞);472300 河南省三门峡市直机关医院中医科(杨亦龙)等 作者:张秋霞 杨亦龙 姚晓泉 常佳慧 陆跃

《国际中医中药杂志》[ISSN:1673-4246/CN:CN11-5398/R]

卷: 38 期数: 2016年01期

页码: 67-71

栏目: 论著

出版日期: 2016-01-11

文章信息/Info

Title: Analysis on professor Gao Zhongying herbal administration experience for chronic atrophic gastritis by using traditional Chinese medicine inheritance support system

作者: 张秋霞 杨亦龙 姚晓泉 常佳慧 陆跃 100069 北京,首都医科大学中医药学院(张秋霞、姚晓泉、常佳慧、陆跃);100700 北京,中国中医科学院博士后流动站(张秋霞);472300 河南省三门峡市直机关医院中医科(杨亦龙)

Author(s): Zhang Qiuxia' target="_blank" rel="external"> Zhang Qiuxia* ;  Yang Yilong;  Yao Xiaoquan;  Chang Jiahui; ' target="_blank" rel="external"> Lu Yue. * School of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, China

关键词: 胃炎; 萎缩性; 方剂分析; 计算机辅助; 名医经验; 高忠英; 数据挖掘; 用药规律

Keywords: Gastritis;  atrophic;  Formula analysis;  computer assisted;  Famous doctor’s experience; Gao Zhongying' target="_blank" rel="external"> Gao Zhongying;  Data mining;  Medication regularity

DOI: 10.3760/cma.j.issn.1673-4246.2016.01.017

摘要: 目的 探讨高忠英治疗慢性萎缩性胃炎的用药规律。方法 以高忠英门诊病历为数据源,利用“中医传承辅助平台(V2.5)”软件构建数据库,采用频数分析、关联规则分析方法进行数据挖掘,确定处方中核心药物组合及药物间的关联规则等。结果 共收集处方60首,包含83味中药,其中使用频次较高的药物包括浙贝母、天花粉、鸡内金等;频次较高的药物组合包括“浙贝母、天花粉”“浙贝母、鸡内金”“天花粉、鸡内金”“浙贝母、莪术”等。获得不同药物组合模式的关联规则447条。结论 高忠英治疗慢性萎缩性胃炎常采用益气健脾、和胃安中的治疗法则;“脾虚胃燥”是萎缩性胃炎病机的关键。

Abstract: Objective To explore the medication rules of Professor Gao Zhongying in treatment of chronic atrophic gastritis on basis of his curative prescriptions. Method Prof. Gao Zhongying clinic medical records were used as data resource. Database was built by using Traditional Chinese Medicine Inheritance Support System (Version 2.5). The core combination and assocical rules among the drugs were confirmed by frequency analysis and assocical rules analysis methods. Results We collected 60 clinical formulas including 83 kinds of Chinese herbs. The highest frequency used simply drugs were Thunberg Fritilary Bulb, Root of Chinese trichosanthes, endothelium corneum gigeriae galli and so on. The most frequency drug combination were "Thunberg Fritilary Bulb, Root of Chinese trichosanthes", "Thunberg Fritilary Bulb, endothelium corneum gigeriae galli", "Root of Chinese trichosanthes, endothelium corneum gigeriae galli", "Thunberg Fritilary Bulb, Curcuma zedoary" and so on. The drug association rules of drug combination were 447 items. Conclusions The medication rules embodied the thoughts of Professor Gao Zhongying of replenishing qi to invigorate the spleen and regulating the stomach to moisten dryness was the main method in treatment of chronic atrophic gastritis and deficiency of spleen and dryness of stomach, which was the key pathogenesis in occurrence and development of chronic atrophic gastritis.

参考文献/References:

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