[论著]自拟活血止痛方联合甘露醇治疗胫腓骨骨折术后患肢肿痛疗效观察

Time:2016-02-22 19:46:23 来源:050700 河北省新乐市中医医院骨2科(高晓鹏、鲁贵生、陈杰、栗宇鹏),手术室(高朝霞)等 作者:高晓鹏 鲁贵生 陈杰 栗宇鹏 高朝霞

《国际中医中药杂志》[ISSN:1673-4246/CN:CN11-5398/R]

卷: 37 期数: 2015年11期

页码: 994-997

栏目: 论著

出版日期: 2015-11-05

文章信息/Info

Title: Curative observation of Huoxue-Zhitong decoction combined with mannitol in the treatment of swelling and pain after operation of tibiofibular fracture

作者: 高晓鹏 鲁贵生 陈杰 栗宇鹏 高朝霞 050700 河北省新乐市中医医院骨2科(高晓鹏、鲁贵生、陈杰、栗宇鹏),手术室(高朝霞)

Author(s): Gao Xiaopeng' target="_blank" rel="external"> Gao Xiaopeng*;  Lu Guisheng;  Chen Jie' target="_blank" rel="external"> Chen Jie;  Li Yupeng; ' target="_blank" rel="external"> Gao Chaoxia. * Department of Second Orthopedicsthe, Xinle Hospital of Traditional Chinese Medicine, Xinle 050700, China

关键词: 骨折固定术' target="_blank" rel="external">

骨折固定术; 内; 疼痛; 手术后; 肿胀; 活血止痛方; ' target="_blank" rel="external">甘露醇

Keywords: Fracture fixation;  internal;  Pain;  postoperative;  Swelling; Huoxue-Zhitong decoction' target="_blank" rel="external"> Huoxue-Zhitong decoction;  Mannitol

DOI: 10.3760/cma.j.issn.1673-4246.2015.11.009

摘要:

目的 评价自拟活血止痛方联合甘露醇治疗胫腓骨骨折术后患肢肿胀、疼痛的临床疗效。方法 将符合入选标准的86例胫腓骨骨折术后患肢肿痛患者按随机数字表法分为2组各43例,对照组采用甘露醇静脉快速滴注,观察组在对照组基础上服用自拟活血止痛方,观察2组术后1、10 d患肢肿胀的缓解程度与视觉模拟量表(visual analogue scale, VAS)评分变化,比较2组消肿、止痛时间并判定临床疗效。结果 术后10 d,观察组患肢肿胀程度[(1.3±0.7)cm比(1.9±0.9)cm,t3.451]、VAS评分[(1.5±0.6)分比(1.9±0.7)分,t2.845]均低于对照组(P值均<0.01)。治疗后,观察组消肿时间[(8.6±1.7)d比(9.8±2.3)d,t2.751]、止痛时间[(5.5±1.4)d比(6.7±1.7)d,t3.573]均较对照组缩短(P值均<0.01)。观察组总有效率为97.7%(42/43),对照组为83.7%(36/43),2组比较差异有统计学意义(χ2=4.961,P=0.026)。结论 自拟活血止痛方联合甘露醇可短缩胫腓骨骨折术后患肢肿痛患者的消肿和止痛时间,有效缓解患肢的肿痛程度。

Abstract: Objective To observe the clinical curative effect of Huoxue-Zhitong decoction combined with mannitol in the treatment of swelling and pain after operation of tibiofibular fracture. Methods 86 patients with swelling after the operation of fracture of tibia and fibula were randomly divided into two groups, with 43 cases in each group. The observation group was treated with intravenous rapid infusion of mannitol, the control group was treated with Huoxue-Zhitong decoction combined with intravenous rapid infusion of mannitol. Swelling, pain visual analogue scale (VAS) score of limb of patients at 1 D and 10 d after operation, time of detumescence and acesodyne and the total efficiency of the treatment between the two groups were compared. Results The indices of the two groups mentioned above at 7 d after the operation significantly decreased, the value in the observation group was lower than the control group (1.3 ± 0.7 cm vs. 1.9 ± 0.9 cm, t=3.451; 1.5 ± 0.6 points vs. 1.9 ± 0.7 points, t=2.845; all P<0.01); The detumescence and acesodyne time of the observation group was shorter than those of the control group (8.6 ± 1.7 d vs. 9.8 ± 2.3 d, t=2.751; 5.5 ± 1.4 d vs. 6.7 ± 1.7 d, t=3.573; all P<0.01), the total efficiency in the observation group was superior to the control group, there were statistically significant differences (97.7% vs. 83.7%; χ2=4.961, P=0.026). Conclusions Huoxue-Zhitong decoction combined with mannitol is effective and safe in the treatment of swelling and pain after operation of tibiofibular fracture.

参考文献/References:

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